Ring expansion of alkynyl cyclopropanes to highly substituted cyclobutenes via a N-sulfonyl-1,2,3-triazole intermediate.
نویسندگان
چکیده
Regioselective ring expansion of alkynyl cyclopropanes to highly substituted cyclobutenes was developed. The reaction involves a copper-catalyzed cycloaddition of an alkyne with an arylsulfonyl azide and a silver-catalyzed carbene formation followed by ring expansion of a cyclopropyl carbene intermediate.
منابع مشابه
Cyclization of sulfide, ether or tertiary amine-tethered N-sulfonyl-1,2,3-triazoles: a facile synthetic protocol for 3-substituted isoquinolines or dihydroisoquinolines.
A facile synthetic method to access 3-substituted isoquinoline or dihydroisoquinoline derivatives has been developed via a novel cyclization reaction of N-sulfonyl-1,2,3-triazole derivatives by thermally induced rearrangement.
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ورودعنوان ژورنال:
- Chemical communications
دوره 49 39 شماره
صفحات -
تاریخ انتشار 2013